Karim Diané reached out to Michael Dorn and Doug Jones, who previously played Worf and Saru, for advice on performing with the heavy prosthetics required for his Klingon character Jay-Den Kraag.

Diané's Klingon prosthetics initially took five hours to apply each day, but the process was reduced to two hours by the end of the first season.

Jay-Den Kraag is noted as Star Trek's first depiction of an openly gay Klingon.

The character of Sam was originally written quite differently, but was rewritten to match Kerrice Brooks's approach after she was cast.

The chancellor role of Nahla Ake was written specifically with Holly Hunter in mind, and the writers were surprised when she agreed to join almost immediately.

Paul Giamatti was cast after expressing his love of Star Trek and his wish to play a Klingon while promoting his film The Holdovers; he was given the first five scripts and allowed to choose from five different guest roles, ultimately picking the villain role despite Kurtzman assuming he'd only want a minor one-episode part.

Ideas for a Starfleet Academy-centered Star Trek project date back decades, including a script commissioned from David Loughery for a potential sixth film in the late 1980s that would have shown young Kirk, Spock, and McCoy at the academy fighting a slavery-themed storyline.

William Shatner and writers Judith and Garfield Reeves-Stevens pitched a TV series called Star Trek: The Academy about teenage versions of Kirk, Spock, and McCoy in 2003, which was rejected by Paramount's Sumner Redstone.

Tawny Newsome, voice of Beckett Mariner on Star Trek: Lower Decks, became the first Star Trek actor hired for a staff writing position on a Star Trek series, after Kurtzman was impressed by her improvisation skills on the Strange New Worlds crossover episode 'Those Old Scientists'.

The atrium set for Starfleet Academy is the largest ever built for a Star Trek series, filling the biggest soundstage in Canada at 45,900 square feet, and includes a mess hall, amphitheater, classrooms, catwalks, trees, and a view of the Golden Gate Bridge.

Filming for the series took place at Pinewood Toronto Studios under the working title 'Ivory Tower', with location shooting in the Uptown area of Waterloo, Ontario.

Despite receiving generally favorable reviews from critics (85% on Rotten Tomatoes), the series was targeted by review-bombing campaigns on Rotten Tomatoes and IMDb after its premiere, with anti-'woke' criticism from figures like Stephen Miller and outlets like The Babylon Bee, drawing comparisons to the review-bombing of Star Wars: The Acolyte.

Robert Picardo reprises his role as the Doctor from Star Trek: Voyager, a character Kurtzman decided to bring back after seeing him work well as a teacher for young cadets in the animated series Star Trek: Prodigy.