Patience is a British-Belgian adaptation of the Franco-Belgian television series Astrid et Raphaëlle, also known as Bright Minds, and was announced in February 2024 by Eagle Eye Drama, PBS Distribution and Beta Film in association with Belgium's Happy Duck Films.

The production received support from the Belgian Tax Shelter, a financial incentive scheme, reflecting the show's cross-border Belgian-British origins.

For the second series, Jessica Hynes joined the cast as a new detective inspector replacing Laura Fraser's character, since Fraser was unavailable to return.

Although the series is set in York, England, only exterior sequences were filmed there, at locations such as Precentor's Court opposite York Minster, Monkgate, The Shambles, Gillygate and Micklegate, while most of the show was actually shot in Belgium.

Location filming for the first series took place in York over just one week, from 23 to 29 April 2024.

The second series had a new writing team led by Amy Shindler and Beth Chalmers, and was filmed in Belgium and York in May 2025.

On Rotten Tomatoes, 85% of 13 critics' reviews were positive, with the consensus praising Ella Maisy Purvis' performance for bringing 'a fresh angle to the detective genre through character rather than plotting.'

Critical reception to series one was mixed, with The Guardian's Lucy Mangan giving it two stars and calling the plot 'preposterous' and the dialogue 'terrible', while The Times' Carol Midgely praised Purvis for not overacting the character's autism.