The North American Being Human is a remake of a BBC series with the same premise, adapted by married writing duo Jeremy Carver and Anna Fricke, who aimed to use elements of the original while creating new characters and storylines.

Because the British original's first season had only six episodes, the North American version had to develop entirely new stories and arcs to fill out its longer 13-episode first season.

The vampire character Aidan is named as an explicit tribute to Irish actor Aidan Turner, who played the vampire Mitchell in the original British series.

The directorial style of the first two episodes followed the original UK pilot and first episode closely, in some cases recreating shots shot-for-shot.

Actor Sam Witwer deliberately watched only the first episode of the British series' second season and avoided the rest so he wouldn't subconsciously mimic Aidan Turner's performance.

The writers and cast intentionally avoided watching anything beyond the first series of the British Being Human even after starting season two, in order to ensure the North American show developed in different directions.

Sam Witwer stressed that despite surface similarities between characters (such as vampire leaders Bishop and Herrick), the North American characters were meant to be distinct from their British counterparts.

The show's first season premiere averaged 1.8 million viewers, making it Syfy's most successful winter scripted series launch since 2005, and by season two the audience was as much as 52% female, a first for the network.