Producer Reiichi Aoki asked director Keitaro Motonaga to direct the anime after re-reading the second volume of the light novel and getting a kaiju-like impression from it; Motonaga reportedly agreed immediately.

During auditions for the character Kurumi Tokisaki, the production staff said that voice actress Asami Sanada won the role the moment she spoke just a single line.

Ayana Taketatsu, who voices Kotori Itsuka, said she struggled during Season 1 with portraying the character's two contrasting 'white mode' and 'black mode' personalities, but found it came naturally as the sequels and film progressed.

Animation production for Season 2 was handed over to the newly founded studio Production IMS, formed by former staff of AIC, while the BS broadcaster changed to BS11.

From Season 3 onward the animation studio changed to J.C.Staff, and the broadcast lineup shifted, with the Chukyo region broadcaster switching to TV Aichi and most independent stations in southern Kanto (other than TOKYO MX) dropping the show.

Season 4's production was influenced by the series' high popularity in China, and animation production moved to studio Geek Toys; the season, originally planned for October 2021, was delayed to April 2022.

The Blu-ray first volume of Season 1 sold 7,171 copies in its first week, ranking 8th on Oricon's weekly Blu-ray anime chart, while Season 2's first volume sold 4,601 copies, also ranking 8th.

At the first Anime Trending Awards held by the American anime review site Anime Trending, the series placed 4th in Best Character Design, 5th in Sequel or New Season Anime of the Year, and 4th in Horror or Suspense/Thriller Anime of the Year.

The film 'Date A Live: Mayuri Judgment' was produced with an original story supervised by original author Kōshi Tachibana, rated G, and earned a box office of about 103 million yen.

Machida City was selected as one of the '88 Anime Pilgrimage Sites in Japan' by the Anime Tourism Association because of its association with Date A Live, leading to collaboration campaigns such as digital stamp rallies tied to Seasons 4 and 5.