The series was unofficially preceded by a 1996 Showtime television movie starring Melissa Joan Hart as 'Sabrina Sawyer,' with different actresses (Charlene Fernetz and Sherry Miller) playing the aunts before the show recast them as Beth Broderick and Caroline Rhea.

Caroline Rhea and Beth Broderick left after season six because Sabrina's college storyline reduced the aunts' importance; Broderick felt Zelda's role had nothing more to offer, while Rhea got her own syndicated talk show, The Caroline Rhea Show.

Nate Richert, who played Harvey, was initially dropped for season 5 to give the show a different college-era look, but the decision was reversed and he returned as a guest before rejoining as a regular in seasons 6 and 7.

David Lascher (Josh) left the show after season 6 reportedly to pursue other projects, leading producers to introduce a new love interest, Aaron, played by Dylan Neal, for the final season.

Trevor Lissauer, who played housemate Miles, was written out after season 6 partly due to fan reception issues and budget cuts for the final season, leaving his character's fate never resolved.

The Spellman residence exterior is a real Victorian mansion located at 64 E. Main St. in Freehold, New Jersey, while Westbridge High School exteriors were filmed at Dwight Morrow High School in Englewood, New Jersey.

The opening credits for the final three seasons were filmed at real Boston-area landmarks including Harvard Bridge, Boston Common, Union Oyster House, the Massachusetts State House, Quincy Market, Newbury Street, Harvard University, Tufts University, and Beacon Hill.

When the show moved from ABC to The WB, it was due to a pay dispute: Viacom wanted a fee increase above $1 million per episode, ABC offered $1.2 million, and The WB won the show by offering only $650,000 per episode but committing to two seasons.

The 1998 soundtrack album, featuring artists like Spice Girls, Backstreet Boys, and Britney Spears plus Melissa Joan Hart's own cover of 'One Way or Another,' was certified Gold in the US and double Platinum in Canada, selling over 700,000 copies worldwide.

An animated spin-off, Sabrina: The Animated Series, featured Melissa Joan Hart's younger sister Emily Hart voicing Sabrina, while Hart herself voiced both aunts; a planned spin-off centered on Salem the Cat was scrapped before airing.