The Pitch pilot was sold on September 8, 2015 by creators Dan Fogelman and Rick Singer, and Fox ordered the pilot to be shot on January 14, 2016 before officially picking up the series on May 10, 2016.

Major League Baseball cooperated in the production of the series, which allowed it to feature a real MLB team, the San Diego Padres.

Ali Larter was cast as agent Amelia Slater on March 10, 2016, replacing Elisabeth Shue who had originally been set for the role.

Kylie Bunbury was cast as lead character Ginny Baker on the same day Fox ordered the pilot, January 14, 2016, while Mark-Paul Gosselaar joined as Mike Lawson in February 2016.

The series was filmed in San Diego, California, with producers planning to use the Padres' real stadium, Petco Park, to shoot scenes set during away games or the off-season.

TV Guide ranked Pitch fourth among its top ten most anticipated new shows of the 2016–2017 season, with critic Liz Rafferty comparing its potential impact to Friday Night Lights.

The show earned a 93% 'Fresh' rating on Rotten Tomatoes from 55 reviews and a 69/100 'generally favorable' score on Metacritic based on 27 critics, but was still canceled by Fox in May 2017 after one season, reportedly due to tough competition from Thursday Night Football.

Showrunner Kevin Falls had planned a second season starting with Spring Training, focusing on Ginny Baker fighting to win back her rookie job after an injury, and a storyline involving a gay player that had already been approved by MLB's department of inclusion.