The series was produced by Jim Krieg, Butch Lukic, and Alan Burnett, and its first season, which aired from 2016 to 2018, ultimately marked the end of the show.

Justice League Action first debuted internationally on Cartoon Network UK on November 26, 2016, before premiering in the United States on Cartoon Network on December 16, 2016.

The show later expanded into a short-form web series called 'Justice League Action Shorts', which began airing on the DC Kids' YouTube channel on June 29, 2017.

The series rolled out internationally over time, premiering on Cartoon Network Australia on March 18, 2017, and on Cartoon Network Philippines on March 25, 2017.

As a promotional tie-in, McDonald's distributed Happy Meal toys based on the show starting September 20, 2016, exclusively in the United States, ahead of the series' actual television premiere.