The show's title refers to the thirty pieces of silver that Judas Iscariot received for betraying Jesus Christ, one of which appears as a mysterious coin driving the plot.

Although Álex de la Iglesia planned for the series to run three seasons, HBO/Max cancelled it in May 2024; the scripts for the already-written third and final season existed and De la Iglesia hoped to find a way to produce them anyway.

Paul Giamatti and Najwa Nimri joined the cast starting with the second season, with Nimri's involvement first revealed when she self-announced it on the red carpet of the 9th Feroz Awards after months of online rumors.

The first season was shot primarily in the village of Pedraza (Segovia province), with additional locations including the Aldeadávila Dam, the Castle of Calatrava la Nueva, the Palace of the Marquis of Santa Cruz, and libraries in Salamanca and Alcalá de Henares, as well as international shoots in Jerusalem, Rome, New York, and Paris; scenes set in Aleppo were actually recreated using Spanish locations.

Season 2 filming began in February 2022 and lasted 27 weeks, taking the production to Spain, Italy, the United States, France, and the United Kingdom, including additional shooting in the city of Toledo.

The series' first episode premiered as part of the Official Section of the Sitges Film Festival and was also screened at the 77th Venice International Film Festival on September 11, 2020, ahead of its television debut.

Season 1 holds a 91% approval rating on Rotten Tomatoes based on 11 critic reviews, with critics praising its blend of horror and absurdity while comparing its Catholic-flavored cosmic horror to the works of William Hope Lovecraft and Hodgson, and its visual style to Luis Buñuel and Alex Cox.

Critic Miguel Ángel Romero noted an implicit reference to the Lovecraftian entity Nyarlathotep in the season finale, and highlighted De la Iglesia's influences from Antonio Mercero, Ridley Scott, and John Carpenter.