The show is a jukebox musical whose soundtrack consists entirely of previously written popular songs, with only two original songs created for the series: 'Crimson Love' in season 2 and 'North Star' in the Christmas film.

Creator Austin Winsberg based Mitch Clarke's illness, progressive supranuclear palsy, in part on his own experiences with his father.

Carmen Cusack was originally cast as Joan in the pilot but was replaced by Lauren Graham in August 2019 before the series began.

Several actors were promoted from recurring to series regular status for season 2, including Kapil Talwalkar, Andrew Leeds, Alice Lee, and Michael Thomas Grant.

Lauren Graham's character Joan was written out in season 2 as moving to Singapore because Graham was busy filming The Mighty Ducks: Game Changers.

Principal photography for the first season took place in Richmond, British Columbia, though the pilot's open-air musical numbers were filmed on location in San Francisco, including the Embarcadero and North Beach.

Mandy Moore, known for her choreography work, served as both a producer and the choreographer for the series.

The 2021 holiday film Zoey's Extraordinary Christmas was shot in Vancouver, with filming running from September 15 to October 8, 2021.

The seven-minute season 1 finale performance of 'American Pie', which followed Mitch's funeral, featured all the lead actors singing individually and in harmony and was filmed in a single continuous shot.

The first season holds a 76% approval rating on Rotten Tomatoes based on 34 reviews, while the second season improved to an 83% approval rating based on 6 critic reviews.